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Mark C Jacobson, MD

Mark C Jacobson, MD

Dr. Jacobson is considered a thought leader in the specialty of Allergy, Asthma, and Immunology. He has been recognized by both Chicago Magazine and Castle Connolly as a Regional Top Doctor since 2016. Dr. Jacobson is a Past President of the Illinois Society of Allergy, Asthma, and Immunology (ISAAI.org). He has also served on its Continuing Education Committee and Executive Board.

Dr Jacobson is Board Certified in both Pediatric and Adult Allegy & Immunology by the American Board of Allergy & Immunology.  Dr. Jacobson has been in private practice since 1995 after completing his Fellowship in Adult and Pediatric Allergy, Asthma, and Immunology at Rush-Presbyterian-St. Luke's Medical Center.

Doctor Jacobson currently teaches family practice residents from Hinsdale Hospital, La Grange Memorial Hospital, and MacNeal Hospital. In addition, he is a fellow and a spokesperson for both the American College of Allergy, Asthma, and Immunology and the American Academy of Allergy, Asthma, and Immunology.

Doctor Jacobson has lectured extensively on the subjects of Allergic Rhinitis, Asthma, Sinusitis, Chronic Cough, Urticaria/Angioedema, Pediatric Allergy, Stinging Insect Hypersensitivity. Dr. Jacobson has staff privileges at Hinsdale Hospital, LaGrange Memorial Hospital, and MacNeal Hospital.

In his free time, he enjoys spending time with his three kids, wife, and friends. He is an avid sports fan and loves following his favorite Chicago sports teams, especially that recent World Series Champion on the North Side. Dr. Jacobson also enjoys reading, mostly non-fiction (so much to learn!), listening to podcasts and working out.

Dr. Jacobson is Proud to be Recognized as a Top Doctor

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Castle Connolly

Dr. Jacobson On CNN - (Watch Video Below)


  • Board Certified
    American Board of Allergy, Asthma, and Immunology
    (A Conjoint Board of the American Academy of Pediatrics and the American Board of Internal Medicine)
    American Board of Internal Medicine
  • Fellowship
    Allergy, Asthma, and Immunology
    Rush-Presbyterian-St. Luke's Medical Center, Chicago, IL
  • Residency
    Internal Medicine
    Northwestern University/Evanston Hospital, Evanston, IL
  • Medical School
    University of Illinois College of Medicine, Chicago, IL
  • Undergraduate
    University of Illinois, Champaign-Urbana
    Bachelor of Science- Biology
  • University Honors
    Bronze Tablet
    Summa Cum Laude,
    Phi Beta Kappa

Clinical Studies

  • Efficacy, Tolerability and Pharmacokinetic Comparison of Immune Globulin Intravenous (Human), 10% (Gammagard Liquid) Administered Intravenously or Subcutaneously Following Administration of Hyaluronidase (rHuPH20) in Subject with Primary Immunodeficiency Diseases: Baxter Protocol No. 160603 2009
  • Pharmacosurveillance Data repository of patients with and without a history of anaphylactic reactions subsequent to Xolair Dosing: Protocol Number: Q4458g. Genentech 2009.
  • A Pilot Study to Test and Refine the Readability of the BAI Patient Label Instructions. IXR-305-04-167. Principal Site Investigator, 2008
  • Salmeterol Multicenter Asthma Research Trial (SMART), Protocol SLGA5011. Principal Site Investigator, 1997